A rare and remarkable one-owner SANTA FE RIVERFRONT home nestled in the highly sought-after Three Rivers Estates. With 270 feet directly on the Santa Fe River, this property boasts two lots totaling approximately 2 acres, offering privacy, space, and unmatched access to Florida’s most iconic spring-fed waters. This 5-bedroom, 2.5-bathroom home has been meticulously maintained, including a brand new roof, and is primed for use as a short-term rental (STR) with its spacious layout and unique charm. Located just a few doors up river from the mouth of the Ichetucknee River, and surrounded by natural beauty, it’s a dream spot for both vacationers and river enthusiasts. Inside, you’ll find a bright and open sitting room with panoramic windows overlooking the river. The main floor features the kitchen/ living room w/ wood burning fireplace and an oversized master suite with room for an office the master bath has dual vanities, a walk-in shower, and a garden tub. There’s an additional half bathroom on the main floor for guests. Upstairs, a loft area connects three additional bedrooms and a full bathroom, and the third floor offers a fifth bedroom or bonus space. The ground level offers ample covered parking, kayak or boat storage, and a perfect party space for entertaining by the water. A private dock leads directly to the Santa Fe, making river days effortless. The home is also equipped with an exterior elevator, providing easy access to the main floor—ideal for luggage, groceries, or those with mobility needs. Just steps away from one of the community’s 9 private riverfront parks, and minutes from the community boat ramp, you can spend your days exploring the Santa Fe, Ichetucknee, and Suwannee Rivers—a legendary trio known for crystal-clear springs, tubing, kayaking, and unmatched natural beauty. Whether you're searching for a private riverfront escape or an income-producing vacation rental, this property checks all the boxes.